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Establishment of Polycomb silencing requires a transient interaction between PC and ESC

Two distinct types of Polycomb complexes have been identified in flies and in vertebrates, one containing ESC and one containing PC. Using LexA fusions, we show that PC and ESC can establish silencing of a reporter gene but that each requires the presence of the other. In early embryonic extracts, w...

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Detalhes bibliográficos
Main Authors: Poux, Sylvain, Melfi, Raffaella, Pirrotta, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312795/
https://ncbi.nlm.nih.gov/pubmed/11581156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.208901
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