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Establishment of Polycomb silencing requires a transient interaction between PC and ESC

Two distinct types of Polycomb complexes have been identified in flies and in vertebrates, one containing ESC and one containing PC. Using LexA fusions, we show that PC and ESC can establish silencing of a reporter gene but that each requires the presence of the other. In early embryonic extracts, w...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Poux, Sylvain, Melfi, Raffaella, Pirrotta, Vincenzo
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2001
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312795/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11581156/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.208901
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