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CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing
Trimethylation of histone H3 lysine 27 (H3K27me3) by Polycomb repressive complex 2 (PRC2) is essential for transcriptional silencing of Polycomb target genes, whereas acetylation of H3K27 (H3K27ac) has recently been shown to be associated with many active mammalian genes. The Trithorax protein (TRX)...
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| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Company of Biologists
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2730368/ https://ncbi.nlm.nih.gov/pubmed/19700617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.037127 |
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