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Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer

Cancer genomic DNA sequences enable identification of all mutations and suggest targets for precision medicine. The identities and patterns of the mutations themselves also provide critical information for deducing the originating DNA damaging agents, causal molecular mechanisms, and thus additional...

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Vydáno v:Breast Cancer Res
Hlavní autor: Harris, Reuben S
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303225/
https://ncbi.nlm.nih.gov/pubmed/25848704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-014-0498-3
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