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APOBEC3B mutagenesis in cancer

Recent evidence has implicated APOBEC3B as a source of mutations in cervical, bladder, lung, head and neck, and breast cancers. APOBEC enzymes normally function in innate immune responses, including those that target retroviruses, suggesting links between mutagenesis, immunity and viral infection in...

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Detalhes bibliográficos
Main Authors: Kuong, Kawai J, Loeb, Lawrence A
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965181/
https://ncbi.nlm.nih.gov/pubmed/23985681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2736
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