Inhibition of monoacylglycerol lipase reduces nicotine withdrawal

BACKGROUND AND PURPOSE: Abrupt discontinuation of nicotine, the main psychoactive component in tobacco, induces a withdrawal syndrome in nicotine-dependent animals, consisting of somatic and affective signs, avoidance of which contributes to drug maintenance. While blockade of fatty acid amide hydro...

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Bibliographic Details
Published in:	Br J Pharmacol
Main Authors:	Muldoon, P P, Chen, J, Harenza, J L, Abdullah, R A, Sim-Selley, L J, Cravatt, B F, Miles, M F, Chen, X, Lichtman, A H, Damaj, M I
Format:	Artigo
Language:	Inglês
Published:	BlackWell Publishing Ltd 2015
Subjects:	Research Papers
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4301695/ https://ncbi.nlm.nih.gov/pubmed/25258021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12948
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Inhibition of monoacylglycerol lipase reduces nicotine withdrawal

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