Inhibition of monoacylglycerol lipase reduces nicotine withdrawal

BACKGROUND AND PURPOSE: Abrupt discontinuation of nicotine, the main psychoactive component in tobacco, induces a withdrawal syndrome in nicotine-dependent animals, consisting of somatic and affective signs, avoidance of which contributes to drug maintenance. While blockade of fatty acid amide hydro...

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Detalles Bibliográficos
Publicado en:Br J Pharmacol
Main Authors: Muldoon, P P, Chen, J, Harenza, J L, Abdullah, R A, Sim-Selley, L J, Cravatt, B F, Miles, M F, Chen, X, Lichtman, A H, Damaj, M I
Formato: Artigo
Idioma:Inglês
Publicado: BlackWell Publishing Ltd 2015
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301695/
https://ncbi.nlm.nih.gov/pubmed/25258021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12948
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