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Spirodi(iminohydantoin) Products from Oxidation of 2′-Deoxyguanosine in the Presence of NH(4)Cl in Nucleoside and Oligodeoxynucleotide Contexts
[Image: see text] Upon oxidation of the heterocyclic ring in 2′-deoxyguanosine (dG), the initial electrophilic intermediate displays a wide range of reactivities with nucleophiles leading to many downstream products. In the present study, the product profiles were mapped when aqueous solutions of dG...
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| Publicado no: | J Org Chem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4301082/ https://ncbi.nlm.nih.gov/pubmed/25539403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo502665p |
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