Identification and Structure–Function Analysis of Subfamily Selective G Protein-Coupled Receptor Kinase Inhibitors

[Image: see text] Selective inhibitors of individual subfamilies of G protein-coupled receptor kinases (GRKs) would serve as useful chemical probes as well as leads for therapeutic applications ranging from heart failure to Parkinson’s disease. To identify such inhibitors, differential scanning fluo...

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Bibliografske podrobnosti
izdano v:ACS Chem Biol
Main Authors: Homan, Kristoff T., Larimore, Kelly M., Elkins, Jonathan M., Szklarz, Marta, Knapp, Stefan, Tesmer, John J. G.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2014
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301037/
https://ncbi.nlm.nih.gov/pubmed/25238254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5006323
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