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Molecular Basis for Small Molecule Inhibition of G Protein-Coupled Receptor Kinases

[Image: see text] Small molecules that inhibit the protein kinase A, G, and C (AGC) family of serine/threonine kinases can exert profound effects on cell homeostasis and thereby regulate fundamental processes such as heart rate, blood pressure, and metabolism, but there is not yet a clinically appro...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Homan, Kristoff T., Tesmer, John J. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301174/
https://ncbi.nlm.nih.gov/pubmed/24984143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5003976
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