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Identification and Characterization of Amlexanox as a G Protein-Coupled Receptor Kinase 5 Inhibitor

G protein-coupled receptor kinases (GRKs) have been implicated in human diseases ranging from heart failure to diabetes. Previous studies have identified several compounds that selectively inhibit GRK2, such as paroxetine and balanol. Far fewer selective inhibitors have been reported for GRK5, a tar...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Homan, Kristoff T., Wu, Emily, Cannavo, Alessandro, Koch, Walter J., Tesmer, John J. G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621012/
https://ncbi.nlm.nih.gov/pubmed/25340299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191016937
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