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Synthesis of pyridine derivatives as potential antagonists of chemokine receptor type 4

A series of pyridine derivatives were synthesized as potential inhibitors of chemokine receptor type 4. This chemokine receptor has been linked to various disease pathways including HIV-1 proliferation, autoimmune disorders, inflammatory diseases, and cancer metastasis. The compounds were tested for...

詳細記述

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書誌詳細
出版年:Heterocycl Comm
主要な著者: Mooring, Suazette Reid, Gaines, Theresa, Liang, Zhongxing, Shim, Hyunsuk
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300533/
https://ncbi.nlm.nih.gov/pubmed/25620839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hc-2014-0041
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