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Symmetrical bis-tertiary amines as novel CXCR4 inhibitors
CXCR4 inhibitors are promising agents for the treatment of cancer metastasis and inflammation. A series of novel tertiary amine derivatives targeting CXCR4 were designed, synthesized, and evaluated. The central benzene ring linker and side chains were modified and optimized to study the structure-ac...
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| Publicado no: | Eur J Med Chem |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4894032/ https://ncbi.nlm.nih.gov/pubmed/27179215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.04.040 |
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