Anti-inflammatory hybrids of secondary amines and amide-sulfamide derivatives

The CXCR4/CXCL12 chemokine axis can chemotactically accumulate inflammatory cells to local tissues and regulate the release of inflammatory factors. Developing novel CXCR4 modulators may provide a desirable strategy to control the development of inflammation. A series of novel hybrids were designed...

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Veröffentlicht in:Eur J Med Chem
Hauptverfasser: Bai, Renren, Sun, Jian, Liang, Zhongxing, Yoon, Younghyoun, Salgado, Eric, Feng, Amber, Oum, Yoonhyeun, Xie, Yuanyuan, Shim, Hyunsuk
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891368/
https://ncbi.nlm.nih.gov/pubmed/29529500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2018.02.085
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