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Development of CXCR4 modulators by virtual HTS of a novel amide-sulfamide compound library
CXCR4 plays a crucial role in recruitment of inflammatory cells to inflammation sites at the beginning of the disease process. Modulating CXCR4 functions presents a new avenue for anti-inflammatory strategies. However, using CXCR4 antagonists for a long term usage presents potential serious side eff...
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| Publicado no: | Eur J Med Chem |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5253094/ https://ncbi.nlm.nih.gov/pubmed/27914361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.11.026 |
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