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Synthesis of pyridine derivatives as potential antagonists of chemokine receptor type 4

A series of pyridine derivatives were synthesized as potential inhibitors of chemokine receptor type 4. This chemokine receptor has been linked to various disease pathways including HIV-1 proliferation, autoimmune disorders, inflammatory diseases, and cancer metastasis. The compounds were tested for...

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Detalhes bibliográficos
Publicado no:Heterocycl Comm
Main Authors: Mooring, Suazette Reid, Gaines, Theresa, Liang, Zhongxing, Shim, Hyunsuk
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300533/
https://ncbi.nlm.nih.gov/pubmed/25620839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hc-2014-0041
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