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Identification of non-Ser/Thr-Pro consensus motifs for Cdk1 and their roles in mitotic regulation of C2H2 zinc finger proteins and Ect2

The cyclin B-dependent protein kinase Cdk1 is a master regulator of mitosis and phosphorylates numerous proteins on the minimal consensus motif Ser/Thr-Pro (S/T-P). At least in several proteins, however, not well-defined motifs lacking a Pro in the +1 position, referred herein to as non-S/T-P motifs...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Suzuki, Kazuhiro, Sako, Kosuke, Akiyama, Kazuhiro, Isoda, Michitaka, Senoo, Chiharu, Nakajo, Nobushige, Sagata, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300507/
https://ncbi.nlm.nih.gov/pubmed/25604483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07929
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