Emi2 Inhibition of the Anaphase-promoting Complex/Cyclosome Absolutely Requires Emi2 Binding via the C-Terminal RL Tail

Emi2 (also called Erp1) inhibits the anaphase-promoting complex/cyclosome (APC/C) and thereby causes metaphase II arrest in unfertilized vertebrate eggs. Both the D-box and the zinc-binding region (ZBR) of Emi2 have been implicated in APC/C inhibition. However, it is not well known how Emi2 interact...

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Main Authors: Ohe, Munemichi, Kawamura, Yoshiko, Ueno, Hiroyuki, Inoue, Daigo, Kanemori, Yoshinori, Senoo, Chiharu, Isoda, Michitaka, Nakajo, Nobushige, Sagata, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836971/
https://ncbi.nlm.nih.gov/pubmed/20089832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-11-0974
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