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The existence of two distinct Wee1 isoforms in Xenopus: implications for the developmental regulation of the cell cycle

In eukaryotic cells, the Wee1 protein kinase phosphorylates and inhibits Cdc2, thereby creating an interphase of the cell cycle. In Xenopus, the conventional Wee1 homolog (termed Xe-Wee1A, or Wee1A for short) is maternally expressed and functions in pregastrula embryos with rapid cell cycles. Here,...

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Autori principali: Okamoto, Kengo, Nakajo, Nobushige, Sagata, Noriyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC126008/
https://ncbi.nlm.nih.gov/pubmed/12006499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.10.2472
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