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Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation
Ribosome profiling data report on the distribution of translating ribosomes, at steady-state, with codon-level resolution. We present a robust method to extract codon translation rates and protein synthesis rates from these data, and identify causal features associated with elongation and translatio...
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Publicado no: | Mol Syst Biol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BlackWell Publishing Ltd
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4300493/ https://ncbi.nlm.nih.gov/pubmed/25538139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20145524 |
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