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Translation efficiency is determined by both codon bias and folding energy
Synonymous mutations do not alter the protein produced yet can have a significant effect on protein levels. The mechanisms by which this effect is achieved are controversial; although some previous studies have suggested that codon bias is the most important determinant of translation efficiency, a...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840511/ https://ncbi.nlm.nih.gov/pubmed/20133581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909910107 |
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