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Translation efficiency is determined by both codon bias and folding energy

Synonymous mutations do not alter the protein produced yet can have a significant effect on protein levels. The mechanisms by which this effect is achieved are controversial; although some previous studies have suggested that codon bias is the most important determinant of translation efficiency, a...

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Detalhes bibliográficos
Main Authors: Tuller, Tamir, Waldman, Yedael Y., Kupiec, Martin, Ruppin, Eytan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840511/
https://ncbi.nlm.nih.gov/pubmed/20133581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909910107
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