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Translation efficiency in humans: tissue specificity, global optimization and differences between developmental stages

Various studies in unicellular and multicellular organisms have shown that codon bias plays a significant role in translation efficiency (TE) by co-adaptation to the tRNA pool. Yet, in humans and other mammals the role of codon bias is still an open question, with contradictory results from differen...

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Bibliografiske detaljer
Main Authors: Waldman, Yedael Y., Tuller, Tamir, Shlomi, Tomer, Sharan, Roded, Ruppin, Eytan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875035/
https://ncbi.nlm.nih.gov/pubmed/20097653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq009
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