Aberrant Hypermethylation of Aldehyde Dehydrogenase 2 Promoter Upstream Sequence in Rats with Experimental Myocardial Infarction

Background. Aldehyde dehydrogenase 2 (ALDH2) plays a crucial role in myocardial protection against ischemia. Downregulation of ALDH2 was evidenced after myocardial infarction and the underlying mechanism is not fully understood. DNA methylation can regulate gene transcription in epigenetic level. We...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Wang, Peng, Shen, Cheng, Diao, Lei, Yang, Zhiyin, Fan, Fan, Wang, Cong, Liu, Xiangwei, Sun, Xiaolei, Dong, Zhen, Zhu, Hong, Ma, Xin, Cao, Quan, Zhao, Xiaona, Ma, Duan, Zou, Yunzeng, Hu, Kai, Sun, Aijun, Ge, Junbo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299765/
https://ncbi.nlm.nih.gov/pubmed/25629048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/503692
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