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Aldehyde dehydrogenase 2 activation ameliorates CCl(4)‐induced chronic liver fibrosis in mice by up‐regulating Nrf2/HO‐1 antioxidant pathway

Mitochondrial aldehyde dehydrogenase 2 (ALDH2) is critical in the pathogenesis of alcoholic liver cirrhosis. However, the effect of ALHD2 on liver fibrosis remains to be further elucidated. This study aimed to demonstrate whether ALDH2 regulates carbon tetrachloride (CCl(4))‐induced liver fibrosis a...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Ma, Xin, Luo, Qin, Zhu, Hong, Liu, Xuejing, Dong, Zhen, Zhang, Kaili, Zou, Yunzeng, Wu, Jian, Ge, Junbo, Sun, Aijun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050510/
https://ncbi.nlm.nih.gov/pubmed/29799157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13677
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