Aberrant Hypermethylation of Aldehyde Dehydrogenase 2 Promoter Upstream Sequence in Rats with Experimental Myocardial Infarction

Background. Aldehyde dehydrogenase 2 (ALDH2) plays a crucial role in myocardial protection against ischemia. Downregulation of ALDH2 was evidenced after myocardial infarction and the underlying mechanism is not fully understood. DNA methylation can regulate gene transcription in epigenetic level. We...

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Библиографические подробности
Опубликовано в: :Biomed Res Int
Главные авторы: Wang, Peng, Shen, Cheng, Diao, Lei, Yang, Zhiyin, Fan, Fan, Wang, Cong, Liu, Xiangwei, Sun, Xiaolei, Dong, Zhen, Zhu, Hong, Ma, Xin, Cao, Quan, Zhao, Xiaona, Ma, Duan, Zou, Yunzeng, Hu, Kai, Sun, Aijun, Ge, Junbo
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299765/
https://ncbi.nlm.nih.gov/pubmed/25629048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/503692
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