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Aberrant reactive aldehyde detoxification by aldehyde dehydrogenase-2 influences endometriosis development and pain-associated behaviors

Endometriosis affects ∼176 million women worldwide, yet on average, women experience pain ∼10 years from symptom onset before being properly diagnosed. Standard treatments (drugs or surgery) often fail to provide long-term pain relief. Elevated levels of reactive aldehydes such as 4-hydroxynonenal (...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: McAllister, Stacy L., Sinharoy, Pritam, Vasu, Megana, Gross, Eric R.
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718385/
https://ncbi.nlm.nih.gov/pubmed/32541390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001949
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