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Mitochondrial aldehyde dehydrogenase-2 deficiency compromises therapeutic effect of ALDH bright cell on peripheral ischemia
The autologous ALDH bright (ALDH(br)) cell therapy for ischemic injury is clinically safe and effective, while the underlying mechanism remains elusive. Here, we demonstrated that the glycolysis dominant metabolism of ALDH(br) cells is permissive to restore blood flow in an ischemic hind limb model...
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| Publicado no: | Redox Biol |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5458766/ https://ncbi.nlm.nih.gov/pubmed/28582728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.05.018 |
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