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Mitochondrial aldehyde dehydrogenase-2 deficiency compromises therapeutic effect of ALDH bright cell on peripheral ischemia

The autologous ALDH bright (ALDH(br)) cell therapy for ischemic injury is clinically safe and effective, while the underlying mechanism remains elusive. Here, we demonstrated that the glycolysis dominant metabolism of ALDH(br) cells is permissive to restore blood flow in an ischemic hind limb model...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Sun, Xiaolei, Zhu, Hong, Dong, Zhen, Liu, Xiangwei, Ma, Xin, Han, Shasha, Lu, Fei, Wang, Peng, Qian, Sanli, Wang, Cong, Shen, Cheng, Zhao, Xiaona, Zou, Yunzeng, Ge, Junbo, Sun, Aijun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458766/
https://ncbi.nlm.nih.gov/pubmed/28582728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.05.018
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