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Mitochondrial aldehyde dehydrogenase-2 deficiency compromises therapeutic effect of ALDH bright cell on peripheral ischemia

The autologous ALDH bright (ALDH(br)) cell therapy for ischemic injury is clinically safe and effective, while the underlying mechanism remains elusive. Here, we demonstrated that the glycolysis dominant metabolism of ALDH(br) cells is permissive to restore blood flow in an ischemic hind limb model...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Redox Biol
Asıl Yazarlar: Sun, Xiaolei, Zhu, Hong, Dong, Zhen, Liu, Xiangwei, Ma, Xin, Han, Shasha, Lu, Fei, Wang, Peng, Qian, Sanli, Wang, Cong, Shen, Cheng, Zhao, Xiaona, Zou, Yunzeng, Ge, Junbo, Sun, Aijun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458766/
https://ncbi.nlm.nih.gov/pubmed/28582728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.05.018
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