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Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan

Aging of biological systems is accompanied by degeneration of mitochondrial functions. Different pathways are active to counteract the processes which lead to mitochondrial dysfunction. Mitochondrial dynamics, the fission and fusion of mitochondria, is one of these quality control pathways. Mitophag...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Bernhardt, Dominik, Müller, Matthias, Reichert, Andreas S., Osiewacz, Heinz D.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298727/
https://ncbi.nlm.nih.gov/pubmed/25601284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07885
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