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Deceleration of Fusion–Fission Cycles Improves Mitochondrial Quality Control during Aging

Mitochondrial dynamics and mitophagy play a key role in ensuring mitochondrial quality control. Impairment thereof was proposed to be causative to neurodegenerative diseases, diabetes, and cancer. Accumulation of mitochondrial dysfunction was further linked to aging. Here we applied a probabilistic...

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Detalhes bibliográficos
Main Authors: Figge, Marc Thilo, Reichert, Andreas S., Meyer-Hermann, Michael, Osiewacz, Heinz D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386171/
https://ncbi.nlm.nih.gov/pubmed/22761564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002576
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