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Deceleration of Fusion–Fission Cycles Improves Mitochondrial Quality Control during Aging

Mitochondrial dynamics and mitophagy play a key role in ensuring mitochondrial quality control. Impairment thereof was proposed to be causative to neurodegenerative diseases, diabetes, and cancer. Accumulation of mitochondrial dysfunction was further linked to aging. Here we applied a probabilistic...

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Detalles Bibliográficos
Autores principales: Figge, Marc Thilo, Reichert, Andreas S., Meyer-Hermann, Michael, Osiewacz, Heinz D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386171/
https://ncbi.nlm.nih.gov/pubmed/22761564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002576
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