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Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan
Aging of biological systems is accompanied by degeneration of mitochondrial functions. Different pathways are active to counteract the processes which lead to mitochondrial dysfunction. Mitochondrial dynamics, the fission and fusion of mitochondria, is one of these quality control pathways. Mitophag...
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| Gepubliceerd in: | Sci Rep |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4298727/ https://ncbi.nlm.nih.gov/pubmed/25601284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07885 |
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