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Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan

Aging of biological systems is accompanied by degeneration of mitochondrial functions. Different pathways are active to counteract the processes which lead to mitochondrial dysfunction. Mitochondrial dynamics, the fission and fusion of mitochondria, is one of these quality control pathways. Mitophag...

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Publicado en:Sci Rep
Autores principales: Bernhardt, Dominik, Müller, Matthias, Reichert, Andreas S., Osiewacz, Heinz D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298727/
https://ncbi.nlm.nih.gov/pubmed/25601284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07885
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