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Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan
Aging of biological systems is accompanied by degeneration of mitochondrial functions. Different pathways are active to counteract the processes which lead to mitochondrial dysfunction. Mitochondrial dynamics, the fission and fusion of mitochondria, is one of these quality control pathways. Mitophag...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4298727/ https://ncbi.nlm.nih.gov/pubmed/25601284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07885 |
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