A Synergistic Dysfunction of Mitochondrial Fission/Fusion Dynamics and Mitophagy in Alzheimer’s Disease

Alzheimer’s disease (AD), the most common form of dementia in the elderly, can have a late-onset sporadic or an early-onset familial origin. In both cases, the neuropathological hallmarks are the same: senile plaques and neurofibrillary tangles. Despite AD having a proteinopathic nature, there is st...

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Detalhes bibliográficos
Main Authors: Santos, Renato X., Correia, Sónia C., Wang, Xinglong, Perry, George, Smith, Mark A., Moreira, Paula I., Zhu, Xiongwei
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923835/
https://ncbi.nlm.nih.gov/pubmed/20463393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-100666
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