Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission

Fanconi anemia (FA) is a rare genetic disorder associated with bone-marrow failure, genome instability and cancer predisposition. Recently, we and others have demonstrated dysfunctional mitochondria with morphological alterations in FA cells accompanied by high reactive oxygen species (ROS) levels....

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Foilsithe in:Oncotarget
Main Authors: Shyamsunder, Pavithra, Esner, Milan, Barvalia, Maunish, Wu, Yu Jun, Loja, Tomáš, Boon, Huat Bay, Lleonart, Matilde E., Verma, Rama S, Krejci, Lumir, Lyakhovich, Alex
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2016
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295412/
https://ncbi.nlm.nih.gov/pubmed/27517150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11161
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