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Regulation of mTOR Activity in Snell Dwarf and GH Receptor Gene-Disrupted Mice
The involvement of mammalian target of rapamycin (mTOR) in lifespan control in invertebrates, calorie-restricted rodents, and extension of mouse lifespan by rapamycin have prompted speculation that diminished mTOR function may contribute to mammalian longevity in several settings. We show here that...
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發表在: | Endocrinology |
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Main Authors: | , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Endocrine Society
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4298324/ https://ncbi.nlm.nih.gov/pubmed/25456069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1690 |
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