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mTOR regulates the expression of DNA damage response enzymes in long‐lived Snell dwarf, GHRKO, and PAPPA‐KO mice

Studies of the mTOR pathway have prompted speculation that diminished mTOR complex‐1 (mTORC1) function may be involved in controlling the aging process. Our previous studies have shown diminished mTORC1 activity in tissues of three long‐lived mutant mice: Snell dwarf mice, growth hormone receptor ge...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Dominick, Graham, Bowman, Jacqueline, Li, Xinna, Miller, Richard A., Garcia, Gonzalo G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242303/
https://ncbi.nlm.nih.gov/pubmed/27618784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12525
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