Regulation of mTOR Activity in Snell Dwarf and GH Receptor Gene-Disrupted Mice

The involvement of mammalian target of rapamycin (mTOR) in lifespan control in invertebrates, calorie-restricted rodents, and extension of mouse lifespan by rapamycin have prompted speculation that diminished mTOR function may contribute to mammalian longevity in several settings. We show here that...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Dominick, Graham, Berryman, Darlene E., List, Edward O., Kopchick, John J., Li, Xinna, Miller, Richard A., Garcia, Gonzalo G.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Growth Hormone-Somatostatin-GRH
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298324/
https://ncbi.nlm.nih.gov/pubmed/25456069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1690
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