Growth Hormone Receptor Antagonist Transgenic Mice Are Protected From Hyperinsulinemia and Glucose Intolerance Despite Obesity When Placed on a HF Diet

Reduced GH levels have been associated with improved glucose metabolism and increased longevity despite obesity in multiple mouse lines. However, one mouse line, the GH receptor antagonist (GHA) transgenic mouse, defies this trend because it has reduced GH action and increased adiposity, but glucose...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Endocrinology
Prif Awduron: Yang, Tianxu, Householder, Lara A., Lubbers, Ellen R., List, Edward O., Troike, Katie, Vesel, Clare, Duran-Ortiz, Silvana, Kopchick, John J., Berryman, Darlene E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Endocrine Society 2015
Pynciau:
Growth Hormone-Somatostatin-GRH
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298328/
https://ncbi.nlm.nih.gov/pubmed/25406017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1617
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