Growth Hormone Receptor Antagonist Transgenic Mice Are Protected From Hyperinsulinemia and Glucose Intolerance Despite Obesity When Placed on a HF Diet

Reduced GH levels have been associated with improved glucose metabolism and increased longevity despite obesity in multiple mouse lines. However, one mouse line, the GH receptor antagonist (GHA) transgenic mouse, defies this trend because it has reduced GH action and increased adiposity, but glucose...

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Dades bibliogràfiques
Publicat a:Endocrinology
Autors principals: Yang, Tianxu, Householder, Lara A., Lubbers, Ellen R., List, Edward O., Troike, Katie, Vesel, Clare, Duran-Ortiz, Silvana, Kopchick, John J., Berryman, Darlene E.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2015
Matèries:
Growth Hormone-Somatostatin-GRH
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298328/
https://ncbi.nlm.nih.gov/pubmed/25406017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1617
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