Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination

How chromatin shapes pathways that promote genome–epigenome integrity in response to DNA damage is an issue of crucial importance. We report that human bromodomain (BRD)-containing proteins, the primary “readers” of acetylated chromatin, are vital for the DNA damage response (DDR). We discovered tha...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genes Dev
Egile Nagusiak: Gong, Fade, Chiu, Li-Ya, Cox, Ben, Aymard, François, Clouaire, Thomas, Leung, Justin W., Cammarata, Michael, Perez, Mercedes, Agarwal, Poonam, Brodbelt, Jennifer S., Legube, Gaëlle, Miller, Kyle M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2015
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298138/
https://ncbi.nlm.nih.gov/pubmed/25593309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.252189.114
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