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Histone demethylase KDM5A regulates the ZMYND8–NuRD chromatin remodeler to promote DNA repair

Upon DNA damage, histone modifications are dynamically reshaped to accommodate DNA damage signaling and repair within chromatin. In this study, we report the identification of the histone demethylase KDM5A as a key regulator of the bromodomain protein ZMYND8 and NuRD (nucleosome remodeling and histo...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Gong, Fade, Clouaire, Thomas, Aguirrebengoa, Marion, Legube, Gaëlle, Miller, Kyle M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496618/
https://ncbi.nlm.nih.gov/pubmed/28572115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201611135
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