Physical and Functional Interactions between the Histone H3K4 Demethylase KDM5A and the Nucleosome Remodeling and Deacetylase (NuRD) Complex

Histone H3K4 methylation has been linked to transcriptional activation. KDM5A (also known as RBP2 or JARID1A), a member of the KDM5 protein family, is an H3K4 demethylase, previously implicated in the regulation of transcription and differentiation. Here, we show that KDM5A is physically and functio...

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Główni autorzy: Nishibuchi, Gohei, Shibata, Yukimasa, Hayakawa, Tomohiro, Hayakawa, Noriyo, Ohtani, Yasuko, Sinmyozu, Kaori, Tagami, Hideaki, Nakayama, Jun-ichi
Format: Artigo
Język:Inglês
Wydane: American Society for Biochemistry and Molecular Biology 2014
Hasła przedmiotowe:
Gene Regulation
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200253/
https://ncbi.nlm.nih.gov/pubmed/25190814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.573725
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