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The NuRD chromatin–remodeling complex regulates signaling and repair of DNA damage

Cells respond to ionizing radiation (IR)–induced DNA double-strand breaks (DSBs) by orchestrating events that coordinate cell cycle progression and DNA repair. How cells signal and repair DSBs is not yet fully understood. A genome-wide RNA interference screen in Caenorhabditis elegans identified egr...

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Detalhes bibliográficos
Main Authors: Smeenk, Godelieve, Wiegant, Wouter W., Vrolijk, Hans, Solari, Aldo P., Pastink, Albert, van Attikum, Haico
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935570/
https://ncbi.nlm.nih.gov/pubmed/20805320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201001048
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