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DNA double strand break repair pathway choice: a chromatin based decision?

DNA double-strand breaks (DSBs) are highly toxic lesions that can be rapidly repaired by 2 main pathways, namely Homologous Recombination (HR) and Non Homologous End Joining (NHEJ). The choice between these pathways is a critical, yet not completely understood, aspect of DSB repair. We recently foun...

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Detalhes bibliográficos
Publicado no:Nucleus
Main Authors: Clouaire, T, Legube, G
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615830/
https://ncbi.nlm.nih.gov/pubmed/25675367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2015.1010946
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