Loss of Keratinocytic RXRα Combined with Activated CDK4 or oncogenic NRAS Generates UVB-induced Melanomas via Loss of p53 and PTEN in the Tumor Microenvironment

Lignende værker

• Ablation of epidermal RXRα in cooperation with activated CDK4 and oncogenic NRAS generates spontaneous and acute neonatal UVB induced malignant metastatic melanomas
  af: Chagani, Sharmeen, et al.
  Udgivet: (2017)
• Loss of nuclear receptor RXRα in epidermal keratinocytes promotes the formation of Cdk4-activated invasive melanomas
  af: Hyter, Stephen, et al.
  Udgivet: (2010)
• RXRα ablation in epidermal keratinocytes enhances UV radiation induced DNA damage, apoptosis, and proliferation of keratinocytes and melanocytes
  af: Wang, Zhixing, et al.
  Udgivet: (2010)
• Retinoid-X-Receptors (α/β) in Melanocytes Modulate Innate Immune Responses and Differentially Regulate Cell Survival following UV Irradiation
  af: Coleman, Daniel J., et al.
  Udgivet: (2014)
• Endothelin-1 is a transcriptional target of p53 in epidermal keratinocytes and regulates UV induced melanocyte homeostasis
  af: Hyter, Stephen, et al.
  Udgivet: (2013)