Retinoid-X-Receptors (α/β) in Melanocytes Modulate Innate Immune Responses and Differentially Regulate Cell Survival following UV Irradiation

Understanding the molecular mechanisms of ultraviolet (UV) induced melanoma formation is becoming crucial with more reported cases each year. Expression of type II nuclear receptor Retinoid-X-Receptor α (RXRα) is lost during melanoma progression in humans. Here, we observed that in mice with melanoc...

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Detalhes bibliográficos
Main Authors: Coleman, Daniel J., Garcia, Gloria, Hyter, Stephen, Jang, Hyo Sang, Chagani, Sharmeen, Liang, Xiaobo, Larue, Lionel, Ganguli-Indra, Gitali, Indra, Arup K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014444/
https://ncbi.nlm.nih.gov/pubmed/24810760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004321
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