Retinoid-X-Receptors (α/β) in Melanocytes Modulate Innate Immune Responses and Differentially Regulate Cell Survival following UV Irradiation

Understanding the molecular mechanisms of ultraviolet (UV) induced melanoma formation is becoming crucial with more reported cases each year. Expression of type II nuclear receptor Retinoid-X-Receptor α (RXRα) is lost during melanoma progression in humans. Here, we observed that in mice with melanoc...

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Главные авторы: Coleman, Daniel J., Garcia, Gloria, Hyter, Stephen, Jang, Hyo Sang, Chagani, Sharmeen, Liang, Xiaobo, Larue, Lionel, Ganguli-Indra, Gitali, Indra, Arup K.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014444/
https://ncbi.nlm.nih.gov/pubmed/24810760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004321
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