RNA interference screening identifies lenalidomide sensitizers in multiple myeloma, including RSK2

To identify molecular targets that modify sensitivity to lenalidomide, we measured proliferation in multiple myeloma (MM) cells transfected with 27 968 small interfering RNAs in the presence of increasing concentrations of drug and identified 63 genes that enhance activity of lenalidomide upon silen...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Blood
Päätekijät: Zhu, Yuan Xiao, Yin, Hongwei, Bruins, Laura A., Shi, Chang-Xin, Jedlowski, Patrick, Aziz, Meraj, Sereduk, Chris, Kortuem, Klaus Martin, Schmidt, Jessica E., Champion, Mia, Braggio, Esteban, Keith Stewart, A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2015
Aiheet:
Lymphoid Neoplasia
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296009/
https://ncbi.nlm.nih.gov/pubmed/25395420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-05-577130
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