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Kinase Regulation by Hydrophobic Spine Assembly in Cancer

A new model of kinase regulation based on the assembly of hydrophobic spines has been proposed. Changes in their positions can explain the mechanism of kinase activation. Here, we examined mutations in human cancer for clues about the regulation of the hydrophobic spines by focusing initially on mut...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Hu, Jiancheng, Ahuja, Lalima G., Meharena, Hiruy S., Kannan, Natarajan, Kornev, Alexandr P., Taylor, Susan S., Shaw, Andrey S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295384/
https://ncbi.nlm.nih.gov/pubmed/25348715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00943-14
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