Deciphering the Structural Basis of Eukaryotic Protein Kinase Regulation

Eukaryotic protein kinases (EPKs) regulate numerous signaling processes by phosphorylating targeted substrates through the highly conserved catalytic domain. Our previous computational studies proposed a model stating that a properly assembled nonlinear motif termed the Regulatory (R) spine is essen...

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Detalhes bibliográficos
Main Authors: Meharena, Hiruy S., Chang, Philip, Keshwani, Malik M., Oruganty, Krishnadev, Nene, Aishwarya K., Kannan, Natarajan, Taylor, Susan S., Kornev, Alexandr P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797032/
https://ncbi.nlm.nih.gov/pubmed/24143133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001680
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