Deciphering the Structural Basis of Eukaryotic Protein Kinase Regulation

Eukaryotic protein kinases (EPKs) regulate numerous signaling processes by phosphorylating targeted substrates through the highly conserved catalytic domain. Our previous computational studies proposed a model stating that a properly assembled nonlinear motif termed the Regulatory (R) spine is essen...

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Détails bibliographiques
Auteurs principaux: Meharena, Hiruy S., Chang, Philip, Keshwani, Malik M., Oruganty, Krishnadev, Nene, Aishwarya K., Kannan, Natarajan, Taylor, Susan S., Kornev, Alexandr P.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797032/
https://ncbi.nlm.nih.gov/pubmed/24143133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001680
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