Laddar...

Kinase Regulation by Hydrophobic Spine Assembly in Cancer

A new model of kinase regulation based on the assembly of hydrophobic spines has been proposed. Changes in their positions can explain the mechanism of kinase activation. Here, we examined mutations in human cancer for clues about the regulation of the hydrophobic spines by focusing initially on mut...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Mol Cell Biol
Huvudupphovsmän: Hu, Jiancheng, Ahuja, Lalima G., Meharena, Hiruy S., Kannan, Natarajan, Kornev, Alexandr P., Taylor, Susan S., Shaw, Andrey S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295384/
https://ncbi.nlm.nih.gov/pubmed/25348715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00943-14
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!